Two teenagers have been charged after a group of masked attackers allegedly broke into an inner west home and stabbed a 16-year-old boy.

Police allege the teens, both aged 15, were part of a group of eight who broke into the Marrickville home just before 5pm on Wednesday and stabbed the 16-year-old.

The 16-year-old was stabbed several times before the group allegedly fled the home, police said. NSW Ambulance paramedics treated him at the scene before taking him to hospital.

Shortly after, police stopped the two 15-year-olds before arresting them and seizing a knife. Six members of the group remain on the run, police say.

One of the boys was charged with a number of offences including affray, enter inclosed land not prescribed premises without lawful excuse, being armed with intent to commit an indictable offence, possessing a knife in public place and participating in a criminal group and contributing criminal activity.

The other was charged with affray, enter inclosed land not prescribed premises without lawful excuse and participating criminal group and contributing criminal activity.

Both boys were granted conditional bail at Newtown police station to appear in a children’s court on May 12.

Members of the group and the 16-year-old boy are believed to be known to each other.