Follow live updates on Pope Leo XIV, the first American pontiff.

For betting types, the conventional wisdom says not to put your money on a pope from the United States.

Yet one American some Vatican watchers say could scrape together enough votes is Cardinal Robert Francis Prevost, 69, a Chicago-born polyglot who is viewed as a churchman who transcends borders. He served for two decades in Peru, where he became a bishop and a naturalized citizen, then rose to lead his international religious order. He now holds one of the most influential Vatican posts.

As ideological camps tussle over whether to continue Pope Francis’ inclusive agenda or return to a conservative doctrinal path, supporters of Cardinal Prevost pitch him as a balanced alternative among the papabili, as likely candidates for the papacy are known.

The Rev. Michele Falcone, 46, a priest in the Order of St. Augustine previously led by Cardinal Prevost, described his mentor and friend as the “dignified middle of the road.”

The cardinal resembles Francis in his commitment to the poor and migrants and to meeting people where they are. He told the Vatican’s official news website last year that “the bishop is not supposed to be a little prince sitting in his kingdom.” Rather, he said, a church leader is “called authentically to be humble, to be close to the people he serves, to walk with them, to suffer with them.”

Cardinal Prevost, appointed by Francis in 2023 to run the Vatican office that selects and manages bishops globally, has spent much of his life outside the United States. Ordained in 1982 at age 27, he received a doctorate in canon law at the Pontifical University of St. Thomas Aquinas in Rome. In Peru, he was a missionary, parish priest, teacher and bishop. As the Augustinians’ leader, he visited orders around the world, and speaks Spanish and Italian.