Police have shot an armed woman after a confrontation in Mulgrave.

The shooting, which occurred about 5.30am on Police Road near Springvale Road, will be investigated by detectives from the armed crime squad.

The 29-year-old woman has been taken to hospital with non-life-threatening injuries to her upper body.

A police statement said the woman was armed in a car that had been allegedly evading police when it was intercepted. After a confrontation, the woman was shot.

A 27-year-old Noble Park man was also arrested at the scene.

An investigation into the matter is under way with oversight by the professional standards command, as is standard practice when a police firearm is discharged.

More to come.

Anyone who witnessed the incident or with further information is urged to contact Crime Stoppers on 1800 333 000 or submit a confidential report online at crimestoppersvic.com.au.